Researchers at New York City-based NYU College of Dentistry designed a topical gel that treats gum disease by suppressing inflammation and altering bacteria makeup in the mouth.
The gel targets the succinate receptor and stops it from activating. In a study, researchers found that applying the gel in mice had reduced gum inflammation, and led to more balanced bacteria levels and less bone loss, according to a Sept. 20 news release shared with Becker’s. The research used human cells and plaque samples in the mice.
Gum disease is one of the most prevalent inflammatory diseases and can lead to bleeding gums, chewing problems and tooth loss, the release said.
The long-term goal of the study is to create a gel and oral strip that can be applied at home, providing an alternative to the current treatments, which can be painful and invasive, according to the release.